Synthesis p. 1451 - 1456 (1997)
Update date:2022-08-03
Topics:
Boelle, Jerome
Schneider, Raphael
Gerardin, Philippe
Loubinoux, Bernard
Reaction of the ethylene acetals of β-nitroenones 3 with isocynaoacetates followed by acidic hydrolysis allowed the synthesis of 3-alkanoylpyrrole-2-carboxylates 9a-f and 7-oxo-4,5,6,7-tetrahydro-2H-isoindole-1-carboxylates 9g-i in good yield. 3-Alkanoyl-4-nitropyrroles 11 a,b were obtained using 3 and tosylmethyl isocyanide.
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Doi:10.1016/j.ejmech.2019.06.029
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(1998)
