Bioorganic and Medicinal Chemistry Letters p. 3027 - 3032 (1997)
Update date:2022-09-26
Topics:
Agoston, Gregory E.
Vaughan, Roxanne
Lever, John R.
Izenwasser, Sari
Terry, Phyllis D.
Newman, Amy Hauck
A novel photoaffinity label for the dopamine transporter (DAT) based on N-substituted 3α-[bis(4'-fluorophenyl)methoxy] tropane has been synthesized in five steps and has been characterized. Preliminary binding studies indicated this ligand bound irreversi
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