Journal of Pharmaceutical Sciences p. 1203 - 1205 (1983)
Update date:2022-09-26
Topics:
Ehrsson
Hassan
A GC-MS technique with selected-ion monitoring is described for the determination of busulfan in plasma. Busulfan is extracted from plasma with methylene chloride and converted to 1,4-diiodobutane. Analysis by GC-MS with selected-ion monitoring (m/z 183) gave a relative standard deviation of ± 4.3% (n = 5) at the 10-ng/ml level.
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