Journal of Heterocyclic Chemistry p. 177 - 181 (1998)
Update date:2022-08-03
Topics:
Kim, Hong-Seok
Koh, Young Kook
Choi, Jun-Hyeak
A series of benzo-crown ethers containing the thiazole subcyclic moity have been synthesized. Reaction of 1,2-bis(thioamidomethyloxy)benzene 2 with ethyl bromopyruvate in ethanol provided 1,2-bis(thiazolyl)benzene 4 (80%) along with thiazole 5 (14%). Reduction of 4 with lithium aluminum hydride followed by mesylation-bromination gave 7. Similar treatment of 5 with lithium aluminum hydride followed by bromination resulted in 12. Benzo-crown ethers 8,9,10, and 13 were prepared from the reactions of 4-bromomethylthiazole derivatives 7 and 12 with catechol and resorcinol derivatives in the presence of potassium hydride.
View MoreZhejiang Sanmei Chemical Industry Co., Ltd
Contact:86-579-87633213
Address:Huchu Industrial Zone, Qingnian Rd., Wuyi County, Zhejiang Prov., China.
Jiaxing Taixin Pharmaceutical Chemical Co., Ltd
Contact:0573-82613601
Address:Chemical Park, Jiaxing, Zhejiang, China
Chengdu Cogon Bio-tech Co., Ltd.
Contact:86-28-85171192
Address:NO.52.YongFeng Rd. Chengdu,610041,P.R.China.
Jiangxi Lanqi Fine Chemical S&T Co., Ltd.
Contact:+86-21-64891143
Address:XinJiShan Industrial Area, Zhangshu City, JiangXi Province, China
Contact:0512-63006287
Address:no.88.YISHENG Road,etdz-WUJIANG,SUZHOU,CHINA
Doi:10.1016/0008-6215(94)90024-8
(1994)Doi:10.1016/S0040-4039(98)00187-7
(1998)Doi:10.1002/hlca.19860690521
(1986)Doi:10.1021/jo9817218
(1998)Doi:10.1016/0040-4020(75)80149-9
(1975)Doi:10.1016/0022-1902(66)80115-X
(1966)
