Synthesis of 3-substituted isocoumarins through acyloxypalladation of o-alkenylbenzoic acids

DOI: 10.1248/cpb.42.1700

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1700 - 1702 (1994)

Update date:2022-08-03

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Authors:

Minami Minami

Nishimoto

Nakamura

Hanaoka Hanaoka

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Article abstract of DOI:10.1248/cpb.42.1700

Cyclization of o-alkenylbenzoic acids in the presence of Pd catalyst and benzoquinone led to 3-substituted isocoumarins in high yield. The isocoumarins obtained were converted to isoquinolones by treatment with primary amines.

Full text of DOI:10.1248/cpb.42.1700

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