Synthesis of (2R)-N-Boc-2-amino-4,4,4-trifluorobutanoic acid using trifluoromethylation of Garner's aldehyde

DOI: 10.1016/S0022-1139(97)00155-3

Source and publish data:

Journal of Fluorine Chemistry p. 79 - 81 (1998)

Update date:2022-08-04

Topics:

Authors:

Qing, Feng-Ling

Peng, Sheng

Hu, Chang-Ming

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0022-1139(97)00155-3

Synthesis of enantiomerically pure (2R)-N-Boc-2-amino-4,4,4-trifluorobutanoic acid (1) is described. The key step is trifluoromethylation of Garner's aldehyde.

Full text of DOI:10.1016/S0022-1139(97)00155-3

Products guided by the article

Product name:(S)-2,2-Dimethyl-4-(2,2,2-trifluoro-1-phenoxythiocarbonyloxy-ethyl)-oxazolidine-3-carboxylic acid tert-butyl ester

Cas No:207118-10-3

R&D Labs maybe for 207118-10-3

Evergreen Chemical Industry Ltd.

Contact:86-553-4918210

Address:6#2-602 Wanhaobailing
SunaTech Inc.

Contact:+86 512 6287 2180

Address:398 Ruoshui Road, Suzhou Industrial Park, Suzhou, Jiangsu, P. R. China
HOST COUNTRY LIMITED

Contact:+852 83038667

Address:Room 1502, 15th Floor, SPA Centre,53-55 Lockhart Road, Wanchai, Hong Kong
YORK CHEMICALS LTD

Contact:+1 (647) 918 5848

Address:2343 BRIMLEY RD., Suite 250
Beijing Harmony Chemical Co., Ltd.

Contact:86-010-84956928

Address:Room 207, Jin feng he B building, No 8 Xin Jie Kou Wai Street, Xi Cheng District, Beijing,PRC. 10008

Relevant to this article

Structure and reactivity of the zero-valent ruthenium complex Ru(1,2-bis(diphenylphosphino)ethane)(CO)₃ and the dicationic ruthenium dimer [Ru₂(1,2-bis(diphenylphosphino)ethane)₂(CO) ₆]²⁺

Doi:10.1016/S0022-328X(97)00731-6
(1998)
Quinuclidinium-imidazolium compounds: Synthesis, mode of interaction with acetylcholinesterase and effect upon Soman intoxicated mice

Doi:10.1007/s002040050504
(1998)
Glycosyltransferase inhibitors: Synthesis of D-threo-PDMP, L-threo- PDMP, and other brain glucosylceramide synthase inhibitors from D- or L- serine

Doi:10.1021/jo980951j
(1998)
Chemical synthesis of (4,6-Pyr)-Gal β1→4GlcNacβ1→3Fucβ1→OMe: A pyruvated trisaccharide related to the cell aggregation of the sponge Microciona prolifera

Doi:10.1080/07328309808002904
(1998)
Synthesis and biology of the conformationally restricted ACPD analogue, 2-aminobicyclo[2.1.1]hexane-2,5-dicarboxylic Acid-I, a potent mGluR agonist

Doi:10.1021/jm970719q
(1998)
Organostannoxane-supported Pd(0) nanoparticles as efficient catalysts for Heck-coupling reactions

Doi:10.1016/j.tetlet.2011.05.006
(2011)

Article Doi