Synthesis of (2R)-N-Boc-2-amino-4,4,4-trifluorobutanoic acid using trifluoromethylation of Garner's aldehyde

DOI: 10.1016/S0022-1139(97)00155-3

Source and publish data:

Journal of Fluorine Chemistry p. 79 - 81 (1998)

Update date:2022-08-04

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Authors:

Qing, Feng-Ling

Peng, Sheng

Hu, Chang-Ming

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Article abstract of DOI:10.1016/S0022-1139(97)00155-3

Synthesis of enantiomerically pure (2R)-N-Boc-2-amino-4,4,4-trifluorobutanoic acid (1) is described. The key step is trifluoromethylation of Garner's aldehyde.

Full text of DOI:10.1016/S0022-1139(97)00155-3

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