Bioorganic and Medicinal Chemistry Letters p. 823 - 828 (1998)
Update date:2022-09-26
Topics:
Patel, Mona
Bacheler, Lee T.
Rayner, Marlene M.
Cordova, Beverly C.
Klabe, Ronald M.
Erickson-Viitanen, Susan
Seitz, Steven P.
Two series of cyclic ureas modified at the P1/P1' residue were prepared and evaluated for HIV protease inhibition and whole cell antiviral activity. Compounds 8b, 10 (3- and 4-pyridylmethyl analogs) and 6b (4-methoxy analog) showed significant improvement in antiviral activity relative to lead compounds DMP323 and DMP450.
View MoreGuangzhou Congen Pharmatec Co.,Ltd.
website:https://www.congenpharma.com
Contact:86-020-82350801
Address:Room 501, Building G11, South China Advanced Materials Innovation Park, 31 Kefeng Road, Science City, Guangzhou, China 510663
Weifang Adde Economic And Trade Co.,LTD.
Contact:86-536-8885548
Address:Room 1402,Wanda Plaza B Block,No.958,Yuanfei Road,Kuiwen District
Zhangjiagang Jianing Import & Export Co.,Ltd.
Contact:086-512-55379012 13913607595
Address:NO.1 Guotai North Road Zhangjiagang Economic Development Zone,215600,Jiangsu,China
Changzhou Ansciep Chemical Co.,Ltd.
Contact:+86 519 8630 5871
Address:A-710 Boan International, 8 East Guangdian Road,Wujin,Changzhou
Taizhou KEDE Chemical.Co.,Ltd.
Contact:86-576-84613060
Address:Jiangkou Chemical Zoon
Doi:10.1080/00945719809351668
(1998)Doi:10.1016/S0968-0896(02)00127-X
(2002)Doi:10.1021/jo701900k
(2007)Doi:10.1016/S0957-4166(98)00087-1
(1998)Doi:10.1002/jhet.5570320532
(1995)Doi:10.1021/ja973464e
(1998)
