Bioorganic and Medicinal Chemistry Letters p. 823 - 828 (1998)
Update date:2022-09-26
Topics:
Patel, Mona
Bacheler, Lee T.
Rayner, Marlene M.
Cordova, Beverly C.
Klabe, Ronald M.
Erickson-Viitanen, Susan
Seitz, Steven P.
Two series of cyclic ureas modified at the P1/P1' residue were prepared and evaluated for HIV protease inhibition and whole cell antiviral activity. Compounds 8b, 10 (3- and 4-pyridylmethyl analogs) and 6b (4-methoxy analog) showed significant improvement in antiviral activity relative to lead compounds DMP323 and DMP450.
View MoreZhejiang Chemicals Import & Export Corporation
Contact:86-571-87043088
Address:No.37,Qingchun Road,Hangzhou,China
Jinan Kaypharm Chemical Co.,Ltd
Contact:86-0531-86986780
Address:Room101,No189-2,Huayuan Road,Jinan City,Shandong Province
Hangzhou Yingshanhua Pigment Chemicals Co.,Ltd.
Contact:+86-0150-58101658
Address:Nanyang Economic DevelopmentZong,Xiaoshan,Hangzhou,China
Nanjing Yuance Industry&Trade Co., Ltd.
website:http://www.njyuance.cn/
Contact:+86-25-85439097
Address:B1702, Aoti Bldg, No. 130, Aoti Avenue, Nanjing, China
Contact:+86-10-83993285
Address:Rm.1708, Haobai Tower, Building 6, No.50, North Road, West Third Ring, Haidian District, Beijing, China
Doi:10.1080/00945719809351668
(1998)Doi:10.1016/S0968-0896(02)00127-X
(2002)Doi:10.1021/jo701900k
(2007)Doi:10.1016/S0957-4166(98)00087-1
(1998)Doi:10.1002/jhet.5570320532
(1995)Doi:10.1021/ja973464e
(1998)
