Synthesis of [5'-2H1]-nucleosides with defined (5'S)/(5'R)-ratios

DOI: 10.1016/S0040-4039(98)00433-X

Source and publish data:

Tetrahedron Letters p. 2873 - 2876 (1998)

Update date:2022-09-26

Topics:

Authors:

Oogo, Yu

Ono, Akira Mei

Ono, Akira

Kainosho, Masatsune

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Article abstract of DOI:10.1016/S0040-4039(98)00433-X

A method for preparing 5'-monodeuterated nucleosides with define (5'S)/(5'R)-ratios, starting from glucose, is described. The 5-oxopentose derivatives, derived from glucose, were treated with LiAlD₄ in the presence of Lil and/or t-amylalcohol t

Full text of DOI:10.1016/S0040-4039(98)00433-X

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