A total synthesis of mycophenolic acid

DOI: 10.1016/S0040-4039(98)00423-7

Source and publish data:

Tetrahedron Letters p. 2881 - 2882 (1998)

Update date:2022-08-05

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Authors:

Covarrubias-Zuniga, Adrian

Gonzalez-Lucas, Armando

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Article abstract of DOI:10.1016/S0040-4039(98)00423-7

A total convergent synthesis of mycophenolic acid 1 from 2-geranyl- dimethyl-1,3-acetonedicarboxylate 2 and 4-pivaloyloxy-2-butynal using a Michael addition-Dieckmann cyclization as key step is described.

Full text of DOI:10.1016/S0040-4039(98)00423-7

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