Novel methodology for the preparation of 5-substituted tetrahydro[2,3- d]pyrimidines

Article abstract of DOI:10.1080/00397919808007022

A convenient, concise route for the preparation of tetrahydropyrido[2,3- d]pydmidines functionalized at the 5-position is presented starting from acyclic aldehydes. Key steps involve a high yielding Knoevenagel condensation, 1,4 conjugate addition with an

Full text of DOI:10.1080/00397919808007022

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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Novel Methodology for the
Preparation of 5-Substituted
Tetrahydro[2,3-D]pyrimidines
Samuel E. Watson a , Edward C. Taylor b &
Hemantkar Patel b
a Department of Chemistry , Long Island University ,
One University Plaza, Brooklyn, N.Y., 11201
b Department of Chemistry , Princeton University ,
Princeton, N. J., 08544-1009
Published online: 20 Aug 2006.
To cite this article: Samuel E. Watson , Edward C. Taylor & Hemantkar Patel (1998)
Novel Methodology for the Preparation of 5-Substituted Tetrahydro[2,3-D]pyrimidines,
Synthetic Communications: An International Journal for Rapid Communication of
Synthetic Organic Chemistry, 28:10, 1897-1905, DOI: 10.1080/00397919808007022
To link to this article: http://dx.doi.org/10.1080/00397919808007022
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