Synthetic Communications p. 1897 - 1905 (1998)
Update date:2022-08-04
Topics:
Watson, Samuel E.
Taylor, Edward C.
Patel, Hemantkar
A convenient, concise route for the preparation of tetrahydropyrido[2,3- d]pydmidines functionalized at the 5-position is presented starting from acyclic aldehydes. Key steps involve a high yielding Knoevenagel condensation, 1,4 conjugate addition with an
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(2014)