Design of multidentate pyrrolic ligands by N-modification: Synthesis of N-monomethyl, monoethyl, dimethyl, trimethyl, and tetramethylporphyrinogens

Article abstract of DOI:10.1016/S0040-4039(98)00537-1

Five possible N-methylated and N-monoethylated meso- octaethylporphyrinogens were prepared by N-alkylation of lithiated meso- octaethylporphyrinogens with alkyl iodides in the presence of crown ether. The crystal structure of 3b was established by X-ray crystal structure analysis.