High-throughput synthesis and direct screening for the discovery of novel hydrolytic metal complexes

DOI: 10.1016/S0960-894X(98)00199-1

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1221 - 1224 (1998)

Update date:2022-09-26

Topics:

Authors:

Berg, Thorsten

Vandersteen, Anthony M.

Janda, Kim D.

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Article abstract of DOI:10.1016/S0960-894X(98)00199-1

A 'combinatorial catalysis' strategy was utilized to both rapidly synthesize organometallic complexes and to screen them for catalytic activity in chemical reactions. The application of this strategy has yielded several metal-complexes that catalyze the hydrolysis of carboxylic acid esters efficiently.

Full text of DOI:10.1016/S0960-894X(98)00199-1

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