Serotonin 5-HT4 receptor agonistic activity of the optical isomers of (+/-)-4-amino-N-[2-(1-azabicyclo[3.3.0]octan-5-yl)ethyl]-5-chloro-2,3- dihydro-2-methylbenzo[b]furan-7-carboxamide.

DOI: 10.1248/cpb.46.1039

Source and publish data:

Chemical and pharmaceutical bulletin p. 1039 - 1043 (1998)

Update date:2022-08-02

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Authors:

Kakigami

Usui Usui

Ikami Ikami

Tsukamoto

Miwa Miwa

Taga Taga

Kataoka Kataoka

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Article abstract of DOI:10.1248/cpb.46.1039

The enantiomers, (R)-(-)-1 and (S)-(+)-1, of (+/-)-4-amino-N-[2-(1-azabicyclo[3.3.0]octan-5-yl)ethyl]-5-chloro-2,3- dihydro-2-methylbenzo[b]furan-7-carboxamide [(+/-)-1] were prepared from optically active benzyl 4-acetylamino-2,3-dihydro-2-methylbenzo[b]

Full text of DOI:10.1248/cpb.46.1039

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