Lipase-mediated diastereoselective and enantioselective acetylations of 3-substituted cyclohexanols

DOI: 10.1016/S0040-4039(97)10705-5

Source and publish data:

Tetrahedron Letters p. 635 - 638 (1998)

Update date:2022-08-04

Topics:

Authors:

Tanikaga, Rikuhei

Morita, Akira

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Article abstract of DOI:10.1016/S0040-4039(97)10705-5

Lipase-mediated acetylation of four diastereomeric and enantiomeric isomers of 3-substituted cyclohexanols 2 has led to an efficient resolution to provide a single stereoisomer, (1R,3S)-cyclohexyl acetate (1R,3S)-3 in a high enantiomeric excess.

Full text of DOI:10.1016/S0040-4039(97)10705-5

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