Solution and solid phase combinatorial synthesis of peptidomimetic library containing diversified α-methylated amino acids

DOI: 10.1016/S0960-894X(98)00279-0

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1665 - 1668 (1998)

Update date:2022-08-05

Topics:

Authors:

Kim, Sang Woong

Shin, You Seung

Ro, Seonggu

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(98)00279-0

A combinatorial peptidomimetic library containing diversified α- methylated amino acids was generated by the Ugi four component condensation (4cc) reaction from acids, amines, isocyanides and ketones in both solution and solid phase synthesis procedures. This one-pot methodology overall gave fair to good yields, which compare well with multi-step syntheses.

Full text of DOI:10.1016/S0960-894X(98)00279-0

Products guided by the article

Product name:2-[Benzhydryl-(2-naphthalen-1-yl-acetyl)-amino]-N-benzyl-3-(4-hydroxy-phenyl)-2-methyl-propionamide

Cas No:212394-82-6

R&D Labs maybe for 212394-82-6

Shanghai Micro-mega Industry Co., Ltd.

Contact:0086-21-34628682;57153848

Address:Rm413,No.413,West Meilong Road, Minhang District,Shanghai P R China
Lian Xing Chemical Co.,Ltd.

Contact:0792-8228321

Address:10TH Floor No.121 binjiang Road Xunyang District
Liaoyang Xinyou Chemical Products Co.,Ltd.

Contact:+86-419-5165433 13604191870

Address:Huishang Road6-1, Hongwei District, Liaoyang, Liaoning, China
Xuzhou Tianrun Chemical Co.,Ltd

website:http://www.tianrunchem.cn

Contact:86-516-83832636

Address:fuxing road
AUSHUN PHARMACEUTICAL TECHNOLOGY CO,.LTD

Contact:+86-25-86883560 15951806178

Address:14 Dayingbi, Zhujiang Rd. East, Nanjing, Jiangsu, China.

Relevant to this article

Electrochemical synthesis of ethyl pentafluoroacetoacetate

Doi:10.1016/S0040-4039(99)00170-7
(1999)
Efficient and stereoselective synthesis of β-trifluoromethyl α,β-unsaturated esters via iron(III) porphyrin-catalyzed olefination of ketones

Doi:10.1021/jo034509z
(2003)
Synthesis, Structure and Reactivity of Molybdenum Imido and Oxo Complexes. X-ray Structure of MoCl3(NAr)L2 (Ar = 2,6-diisopropylphenyl: L = N-2',6'-diisopropyl Phenyl-2,5-dimethyl Benzamide)

Doi:10.1016/S0022-328X(98)00626-3
(1998)
Synthesis of imidazonaphthyridines and -quinolines

Doi:10.3987/COM-98-8187
(1998)
Doi:10.1021/jo01263a042
(1969)
Asymmetric synthesis of (2R,5R)-2,5-diaminohexan-1,6-dioic acid

Doi:10.1016/S0040-4020(98)00492-X
(1998)

Article Doi