Bioorganic and Medicinal Chemistry Letters p. 1665 - 1668 (1998)
Update date:2022-08-05
Topics:
Kim, Sang Woong
Shin, You Seung
Ro, Seonggu
A combinatorial peptidomimetic library containing diversified α- methylated amino acids was generated by the Ugi four component condensation (4cc) reaction from acids, amines, isocyanides and ketones in both solution and solid phase synthesis procedures. This one-pot methodology overall gave fair to good yields, which compare well with multi-step syntheses.
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Doi:10.1016/S0040-4039(99)00170-7
(1999)Doi:10.1021/jo034509z
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(1969)Doi:10.1016/S0040-4020(98)00492-X
(1998)
