A short enantioselective access to 2,3,6-trialkylpiperidines and 5,8- dialkylindolizidines

Article abstract of DOI:10.1016/S0040-4020(98)00566-3

An enantioselective access to 2,3,6-trialkylpiperidines 5 is described. This sequence is illustrated by the four-step syntheses, from salts 1, of piperidine 6 and indolizidines 7 and 8. The overall yields are in the range 10-15%. The stereochemistry of in