Tetrahedron Letters p. 5671 - 5674 (1998)
Update date:2022-08-03
Topics: Derivatives Three-Step Sequence Lysine
Nevill Jr., C. Richard
Angell, Paul T.
Oxidation of carbamates with catalytic RuO4, generated from RuO2 and NaBrO3, provides the corresponding acyl carbamates, which can be reduced with NaBH4 to provide alcohols. Application of this methodology to L-lysine provides (S)-6-hydroxynorleucine derivatives.
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