Tetrahedron Letters p. 7767 - 7770 (1998)
Update date:2022-07-29
Topics:
Gaidarova, Elena L.
Borisenko, Anatoly A.
Chumakov, Taras I.
Mel'nikov, Andrey V.
Orlov, Ivan S.
Grishina, Galina V.
A simple and convenient synthetic approach to the new series of 1,2,3,4,5,6,7,8-octahydro-1,6-naphthyridines 1a-j has been developed. This was achieved via a one-pot process combining metalated 4-piperidinonimine alkylation and intramolecular cyclization.
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