Journal of Medicinal Chemistry p. 4288 - 4300 (1998)
Update date:2022-08-02
Topics:
Augeri, David J.
O'Connor, Stephen J.
Janowick, Dave
Szczepankiewicz, Bruce
Sullivan, Gerry
Larsen, John
Kalvin, Douglas
Cohen, Jerry
Devine, Edward
Zhang, Haichao
Cherian, Sajeev
Saeed, Badr
Ng, Shi-Chung
Rosenberg, Saul
Potent and selective non-thiol-containing inhibitors of protein farnesyltransferase are described. FTI-276 (1) was transformed into pyridyl ether analogue 19. The potency of pyridyl ether 19 was improved by modification of the biphenyl core to that of an
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Doi:10.1021/jo9813336
(1998)Doi:10.1021/jm980303s
(1998)Doi:10.1039/jr9310000529
(1931)Doi:10.1248/cpb.46.1556
(1998)Doi:10.1016/S0040-4020(97)00755-2
(1997)Doi:10.1016/S0020-1693(98)00166-2
(1998)
