Journal of Organic Chemistry p. 8976 - 8982 (1998)
Update date:2022-08-05
Topics:
Khanapure, Subhash P.
Powell, William S.
Rokach, Joshua
The first total synthesis of 5-oxo-12(S)-hydroxy-6(E),8(Z),10(E), 14(Z)- eicosatetraenoic acid (5-oxo-12-HETE) 6 and its 8-trans-isomer 7 is reported. The synthetic 5-oxo-12-HETE 6 and its 8,9-trans-isomer 7 were used to identify their formation in mixtures of platelets and neutrophils by transcellular metabolism.
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Doi:10.1248/cpb.46.1710
(1998)Doi:10.1021/jo981396o
(1998)Doi:10.1016/S0040-4020(98)00938-7
(1998)Doi:10.1016/S0960-894X(98)00560-5
(1998)Doi:10.1021/ja01021a017
(1968)Doi:10.1007/s10600-010-9558-9
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