Synthesis of (2R,3S)-3-hydroxy-2-hydroxymethylpyrrolidine from (4S,5S)-3-benzyl-4-formyl-5-vinyl-2-oxazolidinone

DOI: 10.3987/com-98-8292

Source and publish data:

Heterocycles p. 2263 - 2278 (1998)

Update date:2022-08-04

Topics:

Authors:

Wee, Andrew G. H.

McLeod, Douglas D.

Rankin, Trent J.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.3987/com-98-8292

(4S,5S)-3-BenzyI-4-formyl-5-vinyl-2-oxazolidinone (2), readily prepared via the reductive elimination of the mannose-derived iodo phenyl sulfone (6b), is used in the synthesis of the alkaloid (2R,3S)-3-hydroxy-2-hydroxymethylpyrrolidine (1).

Full text of DOI:10.3987/com-98-8292

Products guided by the article

Product name:(3aS,4R,6R,6aS)-4-Benzenesulfonyl-6-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole

Cas No:220458-81-1

R&D Labs maybe for 220458-81-1

Shanghai doly chemical Co.,Ltd

Contact:+86-21-34716221

Address:No.328,WuHe Roard,MinHang,ShangHai China
Zhuhai Rundu Pharmaceutical co.,Ltd

Contact:+86-756-7630755

Address:No.6,North Airport Road,Sanzao Town,Jinwan District
Santow Laboratory Limited

Contact:+86-371-55981030

Address:Room 1571, Macalline Soho, No.1, Shangdu Road, Zhengzhou, Henan
Chongqing maohuan Chemicals Co., Ltd

website:http://www.bschem.com

Contact:+86 13996103726

Address:Chongqing Nan'an District Tu Town
STAR SYNTHESIS CO.,LIMITED

Contact:+(852) 301-98033

Address:Flat C, 23/F, Lucky Plaza, 315-321 Lockhart Road, Wan Chai, Hong Kong

Relevant to this article

An orthogonally protected CycloTriVeratrylene (CTV) as a highly pre-organized molecular scaffold for subsequent ligation of different cyclic peptides towards protein mimics

Doi:10.1016/j.bmc.2017.05.038
(2017)
Synthesis of a new spin trap: 2-(diethoxyphosphoryl)-2-phenyl-3,4-dihydro-2H-pyrrole 1-oxide

Doi:10.1021/jo981875n
(1999)
Cross-metathesis of biosourced fatty acid derivatives: A step further toward improved reactivity

Doi:10.1002/cssc.201403170
(2015)
3-(4-piperidinyl)- and 3-(8-aza-bicyclo[3.2.1]oct-3-yl)-2-phenyl-1H-indoles as bioavailable h5-HT(2A) antagonists

Doi:10.1016/S0960-894X(00)00559-X
(2000)
Studies on vitamin D (Calciferol)and its analogues. 10. Side chain analogues of 25 hydroxyvitamin D₃

Doi:10.1021/jm00211a002
(1977)
Synthesis and antimalarial activity of new 4-aminoquinolines active against drug resistant strains

Doi:10.1039/c6ra14016e
(2016)

Article Doi