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298-12-4

Basic Information
CAS No.: 298-12-4
Name: Glyoxylic acid
Molecular Structure:
Molecular Structure of 298-12-4 (Glyoxylic acid)
Formula: C2H2O3
Molecular Weight: 74.04
Synonyms: Acetic acid, oxo- (9CI);Glyoxylic acid (8CI);2-oxoacetate;glyoxalate;Glyoxylic;Oxalaldehydic acid;Oxoacetic acid;Acetic acid, oxo-, sodium salt;glyoxylate;alpha-Ketoacetic acid;Formic acid, formyl-;Acetic acid, oxo;Oxoethanoic acid;
EINECS: 206-058-5
Density: 1.384 g/cm3
Melting Point: -93 °C
Boiling Point: 224.601 °C at 760 mmHg
Flash Point: 103.914 °C
Solubility: miscible with water
Appearance: clear yellow solution
Hazard Symbols: IrritantXi,CorrosiveC
Risk Codes: 34-43-41
Safety: 26-36/37/39-45-37/39-24
Transport Information: UN 3265 8/PG 2
PSA: 54.37000
LogP: -0.73010
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Chemistry

The Molecular Structure of Glyoxylic acid (CAS NO.298-12-4):

Empirical Formula: C2H2O3
Molecular Weight: 74.0355 
IUPAC Name: oxaldehydic acid  
Appearance: clear yellow solution
Nominal Mass: 74 Da
Average Mass: 74.0355 Da
Monoisotopic Mass: 74.000394 Da 
Index of Refraction: 1.403
Molar Refractivity: 13.06 cm3
Molar Volume: 53.4 cm3
Surface Tension: 50.2 dyne/cm
Density: 1.384 g/cm3
Flash Point: 103.9 °C
Enthalpy of Vaporization: 50.8 kJ/mol
Boiling Point: 224.6 °C at 760 mmHg
Vapour Pressure: 0.0331 mmHg at 25°C 
Storage temp: 2-8°C
Water Solubility: miscible
InChI
InChI=1/C2H2O3/c3-1-2(4)5/h1H,(H,4,5) 
Smiles
C(C=O)(O)=O 
Product Categories: Pharmaceutical Intermediates
Synonyms: Formylformic Acid ; Oxoethanoic acid ; Oxoacetic acid ; Formylformic acid ; Alpha-Ketoacetic Acid ; Oxalaldehydic Acid  
The conjugate base of Glyoxylic acid (CAS NO.298-12-4) is known as glyoxylate. It  is an intermediate of the glyoxylate cycle, enables organisms, such as fungi, bacteria, and plants to convert fatty acids into carbohydrates .

Uses

 Glyoxylic acid (CAS NO.298-12-4) is used as intermediates of spice, medicine, dyes, plastics and varnish materials,and it also used in pharmacy.

Toxicity Data With Reference

1.    

mmo-sat 200 µg/plate ABCHA6 47,2461,83

2.    

ims-rat LDLo:25 mg/kg

    BSIBAC    Bolletino della Societe Italiana di Biologia Sperimentale. 36 (1960),1937.

Consensus Reports

Reported in EPA TSCA Inventory

Safety Profile

Hazard Codes: CorrosiveCIrritantXi
Risk Statements: 34-43-41 
R34: Causes burns
R43: May cause sensitization by skin contact
R41: Risk of serious damage to the eyes
Safety Statements: 26-36/37/39-45-37/39-24 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S37/39: Wear suitable gloves and eye/face protection
S24: Avoid contact with skin
RIDADR: UN 3265 8/PG 2
WGK Germany: 1
RTECS: MD4550000
HazardClass: 8
PackingGroup: III
Poison by intramuscular route. Mutation data reported. A skin, eye, and mucous membrane irritant. When heated to decomposition it emits acrid smoke and fumes.