Stereoselective synthesis of a versatile intermediate for the total synthesis of mono- and bis-THF containing annonaceous acetogenins

DOI: 10.1016/S0040-4039(98)02222-9

Source and publish data:

Tetrahedron Letters p. 193 - 196 (1999)

Update date:2022-08-03

Topics:

Authors:

Jan Jan

Vig Vig

Rudolph Rudolph

Uckun Uckun

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Article abstract of DOI:10.1016/S0040-4039(98)02222-9

Stereoselective synthesis of epoxy tetrahydrofuran (THF) 1, a versatile synthetic precursor for mono-THF and bis-THF containing annonaceous acetogenins, is reported. Compound 1 was synthesized from tridecanal in 11 steps with an overall yield of 24%. The

Full text of DOI:10.1016/S0040-4039(98)02222-9

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Product name:Toluene-4-sulfonic acid (S)-2-hydroxy-2-[(2R,5R)-5-((R)-1-hydroxy-tridecyl)-tetrahydro-furan-2-yl]-ethyl ester

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