Design and synthesis of simplified sordaricin derivatives as inhibitors of fungal protein synthesis

DOI: 10.1016/S0960-894X(98)00693-3

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 103 - 108 (1999)

Update date:2022-08-04

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Authors:

Cuevas, Juan C.

Lavandera, Jose L.

Martos, Jose L.

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Article abstract of DOI:10.1016/S0960-894X(98)00693-3

A reduction of the tetracyclic skeleton of sordarins and sordaricins to a cyclopentane ring bearing the pharmacophore functional groups led to new derivatives retaining part of their in vitro and whole-cell activity.

Full text of DOI:10.1016/S0960-894X(98)00693-3

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