Tetrahedron Letters p. 117 - 120 (1999)
Update date:2022-07-29
Topics:
Kim, Sun Young
Sung, Nack-Do
Choi, Joong-Kwon
Kim, Sung Soo
1H-Benzotriazol-1-yl methanesulfonate has been found to be an effective reagent in selective mesylation for differentiating amine groups from one another. In a molecule with both primary and secondary amine groups, mesylation only occurred at the primary amine group. When a compound contains both amine and hydroxy groups, the reagent selectively mesylated at the amine groups.
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