The first total synthesis of veiutamine, a new type of pyrroloiminoquinone marine alkaloid

Article abstract of DOI:10.1016/S0040-4039(99)00034-9

The first total synthesis of veiutamine, a new type of pyrroroiminoquinone marine alkaloid bearing a p-hydroxybenzyl substituent at C-6, has been achieved. The key step of the synthesis is 6-selective functionalization of the 1,3,4,5-tetrahydropyrrolo[4,3,2-de]quinoline nucleus via N-Boc-directed lithiation.