Bioorganic and Medicinal Chemistry Letters p. 1029 - 1032 (1999)
Update date:2022-08-02
Topics:
Jinno, Shuji
Okita, Takaaki
Inouye, Kuniyo
A total synthesis of an antioxidant (1) having a benzofuran skeleton was achieved in four steps via the palladium(0)-catalyzed cross-coupling reaction. We also prepared several related compounds bearing a variety of aromatic or heterocyclic rings. Some of these compounds demonstrate more potent than 1 for antioxidative activity using guinea pig liver microsomes.
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