Tetrahedron Letters p. 4121 - 4124 (1990)
Update date:2022-08-03
Topics:
Franck-Neumann, M.
Geoffroy, P.
Miesch, M.
Doerwald, F. Zaragoza
The possibility of achieving convergent syntheses with elaborate carbenes is illustrated by the isobutenylalkynylcarbene II (R = Br).By reaction with 3-cyclohexen-1-one, the endo cyclopropanic adduct IIIa is formed as a major product.Metalation with MeLi, followed by reaction with MeI, proceeds with inversion of configuration ( -> sesquicarene skeleton, XI), or, after protection of the ketofunction, with retention of configuration ( -> isosesquicarene VIII).
View MoreAllyChem Co., Ltd., Dalian, China（BBChem）
Contact:+86-411-62313318/62313328
Address:No.5 of Jinbin Road, Jinzhou New District, Dalian City, Liaoning Province, P.R.China
Shanghai Mokai Pharmaceutical Co.,Ltd
Contact:021-60257269
Address:Rm506,No.915,Zhenbei Road,Shanghai,200333,China
ChangZhou XiaQing Chemical Co., Ltd.
Contact:+86-519-88721665
Address:3# Hengluo Road, Henglin Town, Changzhou City, Jiangsu Province，China
website:http://www.coreychem.com
Contact:+86-371-86658258
Address:Building 10 of Innovation Park, East District of the National University Science Park
Yangling Ciyuan biotech Co., Ltd.
Contact:86-15802970736
Address:2-1804, International Park Mansion, No.2, South Fengdeng Road, Lianhu District
Doi:10.1016/S0022-328X(99)00008-X
(1999)Doi:10.1016/S0040-4039(01)89254-6
(1965)Doi:10.1016/S0040-4020(01)85676-3
(1994)Doi:10.1021/jacs.5b05100
(2015)Doi:10.1016/0021-9517(69)90352-2
(1969)Doi:10.1021/ja00757a033
(1972)
