Bioorganic and Medicinal Chemistry p. 837 - 850 (1999)
Update date:2022-08-05
Topics:
Anaya, Josefa
Gero, Stephane D.
Grande, Manuel
Hernando, Jose Ignacio M.
Laso, Nieves M.
The synthesis of some monocyclic β-lactams (monobactams) by the Staudinger reaction using d-glucosamine propanedithioacetal as chiral auxiliary is reported. The influence of several radicals at C3, C4, and C(1') (sugar moiety) as well as other structural aspects are considered in relation to the antielastase activity. Copyright (C) 1999 Elsevier Science Ltd.
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