Wittig reaction: A new route to α-methoxyketones. Application to the synthesis of simplified analogs of artemisinin

DOI: 10.1016/S0040-4039(98)00688-1

Source and publish data:

Tetrahedron Letters p. 4029 - 4030 (1998)

Update date:2022-08-04

Topics:

Authors:

Hamzaoui, Mohamed

Provot, Olivier

Camuzat-Dedenis, Boris

Moskowitz, Henri

Mayrargue, Joelle

Ciceron, Liliane

Gay, Frederick

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(98)00688-1

C-4 substituted antimalarial Artemisinin analogs were synthesised via an unusual Witrig reaction between methoxymethyltriphenylphosphonium ylide and nitriles.

Full text of DOI:10.1016/S0040-4039(98)00688-1

Products guided by the article

Product name:1-Methoxy-4-{(R)-2-[1-methoxy-meth-(E)-ylidene]-cyclohexyl}-butan-2-one

Cas No:244251-59-0

R&D Labs maybe for 244251-59-0

Phantom-pharma

Contact:

Address:
Jiangsu Mingchem Corporation

website:http://www.mingchem.com/en/index

Contact:0519-85170101-802

Address:Fifth Floor,B of Beihua Buliding,520 Road of Science and Education City,Changwu middle road NO.801,Wujin District,Changzhou,Jiangsu province
Binzhou Holly Pharmaceutical Co.,Ltd.

Contact:74517

Address:No.15 Dapu Road,Huangpu District Shanghai,P.R.China
uni source industries limited

Contact:86 21 3772 9386

Address:Rm.1803,Starry Bldg.1,1505 Meijiabang Road,Shanghai 201620 China
Ningbo Hi-tech Zone Nice-Synth Chemical Industry Ltd.

Contact:+86-(574)-81110986

Address:No. 1210, Building 3, Wante Business Centre, Hi-tech Zone, Ningbo

Relevant to this article

Synthesis of a polyoxadiazole containing the 4-hydroxypyridine group and photo-induced fluorescent imaging on the polymer film

Doi:10.1016/j.reactfunctpolym.2009.12.003
(2010)
Cu(ClO₄)₂·6H₂O catalyzed solvent free per-O-acetylation and sequential one-pot conversions of sugars to thioglycosides

Doi:10.1039/c5ra03461b
(2015)
Bronsted instead of lewis acidity in functionalized MIL-101Cr MOFs for efficient heterogeneous (nano-MOF) catalysis in the condensation reaction of aldehydes with alcohols

Doi:10.1021/ic5006456
(2014)
Reaction of piperidone dicarboxylic acid esters with o-amino-thio-phenol

Doi:10.1002/ardp.19703031113
(1970)
The Direct Cyclization of α-Acylamino-Substituted Hydroxamates to β-Lactams

Doi:10.1021/jo00207a045
(1985)
Doi:10.1038/oby.2000.84
(1932)

Article Doi