A new carvone based construction of the ring-A of taxoids

Article abstract of DOI:10.1016/S0040-4039(99)00902-8

A synthesis of the fully functionalized A-ring of taxoids from the commercially available monoterpenic chiron R-carvone is outlined. In this approach, regio- and stereoselective restructuring of alkyl substituents and functionalities is effected on the periphery while retaining the six membered core of carvone.