Friedel-Crafts type reactions of some activated cyclic ketones with phenol derivatives

Article abstract of DOI:10.1080/00397919908085958

Friedel-Crafts type reactions of phenol derivatives with some cyclic ketones such as ninhydrin (1), alloxan (2), isatin (3), and parabanic acid (4) were examined. 2-Monoaryl- and 2,2-diaryl-1,3-indanedione derivatives were obtained depending on the acid catalyst in the cases of ninhydrin and alloxan. In the case of isatin, the corresponding diarylated derivative was obtained as the sole product in high yields. Parabanic acid was unreactive under the reaction conditions.

Full text of DOI:10.1080/00397919908085958

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Synthetic Communications: An
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Friedel-Crafts Type Reactions of
Some Activated Cyclic Ketones with
Phenol Derivatives
Hyun Nam Song a , Hong Jung Lee a , Hyoung Rae Kim b
Eung K. Ryu b & Jae Nyoung Kim a
,
a Department of Chemistry, Chonnam National University,
Kwangju, 500-757, Korea
b Korea Research Institute of Chemical Technology, Daejeon,
305-606, Korea
Published online: 17 Sep 2007.
To cite this article: Hyun Nam Song , Hong Jung Lee , Hyoung Rae Kim , Eung K. Ryu &
Jae Nyoung Kim (1999) Friedel-Crafts Type Reactions of Some Activated Cyclic Ketones
with Phenol Derivatives, Synthetic Communications: An International Journal for Rapid
Communication of Synthetic Organic Chemistry, 29:19, 3303-3311
To link to this article: http://dx.doi.org/10.1080/00397919908085958
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