Archiv der Pharmazie p. 709 - 715 (1992)
Update date:2022-08-02
Topics:
Schwieger
Unterhalt
Phosphoramidic dichlorides 3 are synthesized by nucleophilic attack of methyl 2-(1-ethylenimino)-alkanoates 1 on POCl3 or by the reaction of amino acid methyl ester hydrochlorides 2 with POCl3. Subsequent treatment of 3 with ethylenimine affords the TEPA-analogs 4, and with 3-(1-ethylenimino)-1-propanol (6) the IFOSFAMID analogous 1,3,2-oxaza-phosphorines 5, the cytostatic activity of which was tested in the P388-leukemia of the CD2F1-mouse.
View MoreContact:0027-717-456976
Address:2ND FLOOR, 325 VAUSE ROAD, OVERPORT, 4001, SOUTH AFRICA
shanghai hekang chemical co.ltd
Contact:021-54173790
Address:328 WuHe Road, Building #A, 2nd Floor, Minhang, Shanghai 201109, China
Nanjing FNAT Chemical Co.,Ltd.
Contact:86-25-86442672
Address:No.128 Lushan Road, Jianye District, Nanjing City, Jiangsu Province, China
Jintan Jinnuo Chemical Co., Ltd.
Contact:+86-519-80199901
Address:Room 1804, Building 1, Huacheng Business Plaza, Jintan, Jiangsu, China
Hebei Think-Do Environment Co., Ltd
website:http://www.thinkdo-environment.com
Contact:0311-86510809
Address:No 6, Shilian Middle Street, Circular Chemical Industry Park
Doi:10.1055/s-1999-2875
(1999)Doi:10.1039/a901521c
(1999)Doi:10.1107/S010827019900757X
(1999)Doi:10.1016/S0040-4039(99)01241-1
(1999)Doi:10.1021/jo000068x
(2000)Doi:10.1002/hlca.19800630848
(1980)
