Bioorganic and Medicinal Chemistry Letters p. 687 - 690 (1998)
Update date:2022-08-04
Topics:
Ghosh, Arun K.
Kincaid, John F.
Cho, Wonhwa
Walters, D. Eric
Krishnan
Hussain, Khaja Azhar
Koo, Yumee
Cho, Hanna
Rudall, Clare
Holland, Louis
Buthod, Jim
Design and synthesis of a series of very potent nonpeptide HIV protease inhibitors are described. The inhibitors are derived from novel high affinity P2-ligands and (R)-(hydroxyethylamino)sulfonamide isostere.
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