Bioorganic and Medicinal Chemistry Letters p. 2973 - 2976 (1999)
Update date:2022-08-05
Topics:
Laub, Joanne B.
Greenlee, Mark L.
DiNinno, Frank
Huber, Joann L.
Sundelof, Jon G.
A series of amidinium-substituted 2-dibenzofuranylcarbapenems with potent activity against MRSA has been synthesized via a Stille cross-coupling reaction. These new carbapenems show reduced serum protein binding and improved in vivo efficacy as a conseque
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