The synthesis and anti-MRSA activity of amidinium-substituted 2-dibenzofuranylcarbapenems

DOI: 10.1016/S0960-894X(99)00526-0

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2973 - 2976 (1999)

Update date:2022-08-05

Topics:

Authors:

Laub, Joanne B.

Greenlee, Mark L.

DiNinno, Frank

Huber, Joann L.

Sundelof, Jon G.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(99)00526-0

A series of amidinium-substituted 2-dibenzofuranylcarbapenems with potent activity against MRSA has been synthesized via a Stille cross-coupling reaction. These new carbapenems show reduced serum protein binding and improved in vivo efficacy as a conseque

Full text of DOI:10.1016/S0960-894X(99)00526-0

Products guided by the article

Product name:(5R,6S)-3-[4-(N-Methylcarbamimidoyl)-dibenzofuran-2-yl]-7-oxo-6-((R)-1-trimethylsilanyloxy-ethyl)-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester

Cas No:253268-64-3

R&D Labs maybe for 253268-64-3

ChengduChroma-BiotechCo.,Ltd.

Contact:86-28-61993785

Address:No.70-13-21, North Section, Erhuan
Airsea(Taizhou) Pharmaceutical Limited(expird)

Contact:+86-576-88057622

Address:Dubei, Duqiao, Linhai, Taizhou, Zhejiang, China Zip: 317016
Shangyu Sanhechemicals Co.,LTD.

Contact:86-0571-56696839

Address:Num.2952,Nanhuan Road,Binjiang District,Hangzhou,China
HANGZHOU FOREWIN PHARMA CO., LTD

Contact:+86-571-89053961

Address:hangzhou
jintan yufan Medicine Raw materials Co.,Ltd.(expird)

Contact:86-519-82808282

Address:6th,Jincheng Huangzhuang

Relevant to this article

Doi:10.1021/ja01600a044
(1956)
Chromatography-free enzymatic kinetic resolution of secondary alcohols

Doi:10.1055/s-0029-1216997
(2009)
Synthesis and pharmacology of 1-deoxy analogs of CP-47,497 and CP-55,940

Doi:10.1016/j.bmc.2007.09.033
(2008)
Stereoselective synthesis and some properties of new chlorodiorganotin- substituted macrodiolides

Doi:10.1021/om200987t
(2012)
Selected substituent effects on the rate and efficiency of formation of an eight-membered ring by RCM

Doi:10.1021/jo702726b
(2008)
Pd-P(t-Bu)₃-catalyzed consecutive cross-coupling of p-phenylenedizinc compound with two different electrophiles leading to unsymmetrically 1,4-disubstituted benzenes

Doi:10.1021/jo702103r
(2008)

Article Doi