A versatile synthesis of tetraester polyamine lipids for gene transfection

DOI: 10.1016/S0040-4039(99)01934-6

Source and publish data:

Tetrahedron Letters p. 8985 - 8988 (1999)

Update date:2022-08-05

Topics:

Authors:

Lizarzaburu, Mike E.

Kurth, Mark J.

Nantz, Michael H.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(99)01934-6

The preparation of polyamine lipids via Michael addition of diamines to tetraester bisacrylates is described. A new pentaerythritol protection strategy enabled the synthesis of a bis(p-methoxybenzyl)diether diol which was used to prepare the saturated and unsaturated diester cores.

Full text of DOI:10.1016/S0040-4039(99)01934-6

Products guided by the article

Product name:2,2-bis[{(4-methoxybenzyl)oxy}methyl]propane-1,3-diol

Cas No:256341-02-3

R&D Labs maybe for 256341-02-3

CHEM PLUS

Contact:0027-717-456976

Address:2ND FLOOR, 325 VAUSE ROAD, OVERPORT, 4001, SOUTH AFRICA
Fuxin Jintelai Fluorin Chemical Co., Ltd.

Contact:+86-0418-8229599

Address:, 7th Huagong Road, Fluorine industry development zone (Yimatu Town,Fumeng County),Fuxin City, Liaoning Province, China
Deer Chemicals Co., Ltd.

Contact:+86-13666670345

Address:Agricultural Development Zone, Haining, Jiaxing, Zhejiang
SJZ Chenghui Chemical Co., Ltd.

Contact:86-311-87713916

Address:no.368 youyi north avenue
Quzhou Ruiyuan chemical Co., Ltd

Contact:+86-570-3039321/3039361/3039308

Address:18# Huayang Road,Quzhou High-tech Industrial Park, Zhejiang China.

Relevant to this article

Catalytic Asymmetric Hydrocarboxylation and Hydrohydroxymethylation. A Two-Step Approach to the Enantioselective Functionalization of Vinylarenes

Doi:10.1021/jo9914216
(1999)
Synthesis of chiral N-trifluoroacetyl-methionine derivatives and applying them as acyl donors for Friedel-Crafts acylation

Doi:10.24820/ark.5550190.p010.815
(2019)
A novel methodology for preparing 5-chloro- and 5-bromotryptamines and tryptophans, and its application to the synthesis of (±)-bromochelonin B

Doi:10.3987/com-99-8721
(1999)
Doi:10.1021/jo00836a012
(1970)
Synthesis and anion binding ability of metacyclophane-based cyclic thioureas

Doi:10.1246/cl.1998.835
(1998)
Alkylation of 1-phenyl-3,5-disubstituted pyrazoles with polyfluorinated aliphatic aldehydes: Properties of 1-phenyl-4-(1-hydroxypolyfluoroalkyl)pyrazole derivatives

Doi:10.1016/S0022-1139(99)00212-2
(2000)

Article Doi