European Journal of Organic Chemistry p. 3175 - 3178 (1999)
Update date:2022-08-02
Topics:
Higuchi, Ryuichi
Mori, Takeshi
Sugata, Tetsuji
Yamada, Koji
Miyamoto, Tomofumi
Two simple sea cucumber ganglioside analogs 8 (NeuAcα2→6 Glcβ 1→1 docosanol) and 9 (NeuAcβ2→6 Glcβ 1→1 docosanol), containing a long-chain alcohol as a mimic of ceramide, have been synthesized. Coupling of the methyl 2-thioglycoside derivative of N-acetylneuraminic acid S with docosyl glucoside derivative 3 afforded the protected ganglioside analogs 6 and 7, which were deprotected to give the corresponding ganglioside analogs 8 and 9, respectively. The 13C-NMR data obtained for these anomers 8 and 9 should prove useful for the determination of anomeric configurations of sialic acid residues in gangliosides.
View MoreContact:+86-512-69561895
Address:No.111, Building A4, 218 Xinghu Street, Suzhou Industrial Park, P. R. China
Penglai Qianwei Chemical Co., Ltd.
Contact:86-535-3357802
Address:Shahelu (north), Penglai, Shandong, China
Changsha Goomoo Chemical Technology Co.Ltd
Contact:+86-731-82197655
Address:No.649,Chezhan Rd.(N),Changsha,Hunan,China
Nanjing Chemlin Chemical Co., Ltd.
website:http://www.echemlin.cn
Contact:+86-25-83697070
Address:Rm.902 Longyin Plaza, No. 217 Zhongshan Rd.(N) Nanjing 210009,China
Contact:86 513 85512619
Address:Rm.1306, Building A, Wenfeng Mansion,168 Gongnong Road, Nantong Jiangsu China
Doi:10.1039/b702197f
(2007)Doi:10.1021/ic060831r
(2006)Doi:10.1021/ol061132l
(2006)Doi:10.1021/ol0616539
(2006)Doi:10.1080/15257770600793851
(2006)Doi:10.1021/jm0611509
(2007)