Bioorganic and Medicinal Chemistry Letters p. 3133 - 3136 (1998)
Update date:2022-09-26
Topics:
Smith III, Amos B.
Sasho, Setsuya
Barwis, Bari A.
Sprengeler, Paul
Barbosa, Joseph
Hirschmann, Ralph
Cooperman, Barry S.
A tetrahydropyran-based inhibitor (2) of mammalian ribonucleotide reductase (mRR) has been designed and synthesized based on the heptapeptide, N-AcFTLDADF (1), corresponding to the C-terminus of the R2 subunit of mRR. Inhibition studies revealed that 2 is indeed a competent inhibitor, albeit less potent than 1.
View MoreAnhui Sholon New Material Technology Co., Ltd.
website:http://www.sholonchem.com
Contact:+86-550-5261666
Address:4/F Block B, Beijing Chemical Building.No.520 Tianrun Road ,Science & Education Town Wujin District, Changzhou City Jiangsu Province
Shandong Ailitong New Material Co.,Ltd
Contact:+86-536-3226266
Address:zhongjia village, putong town , qingzhou city,Shandong Province,China
Evergreen Chemical Industry Ltd.
Contact:86-553-4918210
Address:6#2-602 Wanhaobailing
ShangHai BMG Chemical Co., Ltd
Contact:+86-13524845543
Address:Room 602, no 291 sikai road shanghai
Wuhan Silworld Chemical Co.,Ltd
website:http://www.silworldchemical.com
Contact:+86-27-85613400
Address:No.198 jiangjun Road, Wuhan,China 430033
Doi:10.1016/S0040-4039(99)02297-2
(2000)Doi:10.1039/DT9870002723
(1987)Doi:10.1021/ol005504g
(2000)Doi:10.1021/ol0056832
(2000)Doi:10.1016/S0040-4020(01)92757-7
(1970)Doi:10.1023/A:1015022032506
(2002)
