X=Y-ZH Systems as potential 1,3-dipoles. Part 47. Tandem nucleophilic substitution-1,3 dipolar cycloaddition reactions of oximes with epoxides and dipolarophiles

Article abstract of DOI:10.1016/S0040-4020(97)00838-7

Regiospecific nucleophilic substitution reactions involving attack of the nitrogen atom of oximes on epoxides are used to generate nitrones which are then trapped in 1,3-dipolar cycloaddition reactions. These tandem processes are shown to be flexible and