An efficient asymmetric route to eudesmane acids. Total synthesis of (+)-12-hydroxy-α-cyperone, (+)-12-oxo-α-cyperone and (+)-3-oxoeudesma-4,11(13)-dien-12-oic acid

Article abstract of DOI:10.1016/0957-4166(96)00335-7

An efficient asymmetric synthesis of (+)-3-oxoeudesma-4,11(13)-dien-12-oic acid 4, (+)-12-hydroxy-α-cyperone 6 and (+)-12-oxo-α-cyperone 7 from (+)-dihydrocarvone 5 is described, which involves a novel diastereoselective preparation of (+)-α-cyperone 8.