Journal of Heterocyclic Chemistry p. 343 - 348 (2000)
Update date:2022-08-05
Topics:
Poszavacz, Laszlo
Simig, Gyula
Cyclization of N-acyl-2-hydroxy-2-(trifluoromethyl)arylethylamines 4 under Pictet-Gams conditions afforded 2-oxazolines 5 instead of the expected isoquinolines 6. The effect of the trifluoromethyl group on the result of the reaction is discussed.
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