Tetrahedron p. 15711 - 15720 (1998)
Update date:2022-08-03
Topics: Protonation Workup and Isolation Preparation of 2-(1-iminoalkyl) phenols Formation of the Dianion Alkylation of the Dianion
Cimarelli, Cristina
Palmieri, Gianni
A method has been developed for the almost exclusive C-alkylation of the 2-(l-liminoalkyl) phenols 1, important organic compounds with a range of employment, which allows the preparation of complex derivatives 4 with good yields starting from easily available materials. The operational simplicity of this method take advantages in providing a variety of alkylated 2-acyl phenols 5 by an easy hydrolysis of the 2-(1-iminoalkyl) phenols 4.
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