Synthesis and anticonvulsant activity of some 1,2,3,3a-tetrahydropyrrolol[2,1-b]benzothiazol-1-ones and pyrrolo[2,1-b]thiazole analogues

Article abstract of DOI:10.1016/0223-5234(94)90038-8

Tetrahydropyrrolo[2,1-b]benzothiazol-1-ones 2a-1 and its analogues 3a-d were synthesized and tested as anticonvulsant agents. Some of the compounds were effective against bicuculline-induced seizures in mice. Binding studies with the prepared compounds us