Tetrahedron Letters p. 1053 - 1056 (2001)
Update date:2022-09-26
Topics:
Takahashi, Yoshiaki
Nakayama, Hitoshi
Katagiri, Keiki
Ichikawa, Kumi
Ito, Nobuhiro
Takita, Tomohisa
Takeuchi, Tomio
Miyake, Toshiaki
Optically pure 1D-chiro-inositol (DCI) has been synthesized from optically inactive myo-inositol practically in four steps. The crystalline nature of most intermediates and the utilization of inexpensive reagents facilitate the economical mass production of DCI, which is expected to be used in the future for treatment of Type 2 diabetes and polycystic ovary syndrome (PCOS).
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