Organic Letters p. 2588 - 2591 (2017)
Update date:2022-08-03
Topics: Functionalization Cascade reaction Workup C-H Activation Choice of Starting Material
Lv, Ningning
Chen, Zhengkai
Liu, Yue
Liu, Zhanxiang
Zhang, Yuhong
An efficient and expeditious protocol for the synthesis of diverse difunctionalized indenones through rhodium-catalyzed C-H activation and multistep cascade reaction of benzimidates and alkenes has been developed. The transformation involves the cleavage and formation of multiple bonds in one pot under mild reaction conditions, and Mn(OAc)2 plays an important role in the reaction.
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