Synthesis and preliminary pharmacological evaluation of analogues of caracasanamide, a hypotensive natural product

DOI: 10.1016/0960-894X(96)00079-0

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 653 - 658 (1996)

Update date:2022-07-30

Topics:

Authors:

Corelli, Federico

Dei, Donate

Delle Monache, Giuliano

Botta, Bruno

De Luca, Carlo

Carmignani, Marco

Volpe, Anna Rita

Botta, Maurizio

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0960-894X(96)00079-0

Some analogues of the hypotensive agent caracasanamide have been synthesized and tested in vivo for cardiovascular effects. Derivative 2c emerged as the most interesting compound in the series. Structure-activity relationship is also discussed.

Full text of DOI:10.1016/0960-894X(96)00079-0

Products guided by the article

Product name:C₂₈H₄₄N₄O₆

Cas No:365568-13-4

R&D Labs maybe for 365568-13-4

Jiangxi Province Bethel Pharmaceutical Co., Ltd.

Contact:+86-795-259 3456 ，+86-15957688008 13566650571

Address:Huangjindui Chemical Park， Shanggao County ，Yichun city，Jiangxi Province
Chemvon Biotechnology Co. Ltd.

website:http://www.chemvon.com

Contact:86-21-58550039;86-21-31268550-8004

Address:Suite B-10#, 6999 Chuansha Road, Pudong District, Shanghai 201202, China
NanJing KaiHeng Chemical CO., LTD.

Contact:+86-25-85768391

Address:RM.1704, D, WANDA PLAZA, NO.110, MIDDLE JIANGDONG ROAD, NANJING, CHINA
Huaihua Baohua Biotechnology Co.,Ltd

website:http://www.baochengchem.com

Contact:86-519-82698291

Address:HouYang chemical development zone,Jintan,Jiangsu,China (213200)
Dongtai Xinyuan Chemical Co., Ltd.

Contact:+86-21-56733000

Address:404F, 99Nong No.117 Zhongtan Rd. Shanghai

Relevant to this article

Total synthesis of cyclic ADP-carbocyclic-ribose, a stable mimic of Ca²⁺-mobilizing second messenger cyclic ADP-ribose

Doi:10.1021/ja010756d
(2001)
Alkylation-Terminated Catellani Reactions Using Alkyl Carbagermatranes

Doi:10.1002/anie.202008482
(2020)
Discovery and SAR of a novel series of Natriuretic Peptide Receptor-A (NPR-A) agonists

Doi:10.1016/j.bmcl.2017.09.028
(2017)
Reactions of phenylenedioxytrihalophosphoranes with arylacetylenes: III. Features of reactions of 5,6-Dihalo-2-chlorobenzo[d]-1,3,2-dioxaphosphole 2,2-Dichloride with arylacetylenes

Doi:10.1023/A:1012381423101
(2001)
Novel phosphorus-silicon synergistic flame retardants: Synthesis and characterization

Doi:10.1016/j.cclet.2012.04.024
(2012)
Control of Regioselectivity in the Alkylation of 2-Trimethylsilyl-2,5-dihydrothiophene 1,1-Dioxide. A Route for 2,2-Dialkylation

Doi:10.1039/c39870000934
(1987)

Article Doi