Telluro-directed regiospecific and highly stereoselective reaction of ethyl 5-telluro-(2E,4Z)-pentadienoate with organocopper reagents

Article abstract of DOI:10.1016/S0040-4039(97)10571-8

Ethyl 5-telluro-(2E,4Z)-pentadienoate 2, which is prepared by the Wittig olefination of (Z)-β-telluroacrolein 1, reacted very rapidly with organocuprates 3 at -78°C to form exclusively the corresponding 5-substituted products 4 with high stereoselectivity