Phosphorus, Sulfur and Silicon and the Related Elements p. 363 - 376 (2006)
Update date:2022-08-04
Topics:
Haikou, Maria N.
Ioannou, Panayiotis V.
Triaryl trithioarsenites, (ArS)3As, are oxidized by air to As2O3 and ArSSAr. In two cases the parent "thiol" (pyrid-2-thione and 1-hydroxypyrid-2-thione) is coproduced. The oxidation, in nonprotic solvents, is favored by electron-withdrawing groups at the para position of the phenyl group. The products obtained in nonprotic solvents were rationalized by assuming that the binding of the triplet dioxygen to arsenic(III) gives a triplet diradical, (ArS)3As-O-O, or an arsenadioxirane, (ArS)3As(O2), intermediate, which decomposes after nucleophilic attack by another (ArS)3As molecule. In protic solvents a zwitterion, (ArS)3As+-O-O-, and in the presence of moisture a hydroperoxy arsenic(V) compound, (ArS) 3As(OH)-O-OH, may be intermediates in the air oxidation of some aromatic trithioarsenites. These data tend to indicate that arsenic(III) bound to suitable groups can directly bind dioxygen, a property which may have implications in chemotherapy and carcinogenesis. Copyright Taylor & Francis Group, LLC.
View MoreContact:+1-416-493-6870
Address:Toronto, Canada
Contact:+86-22-83718541
Address:32th Floor, Rongqiao Center Intersection of Changjiang Road and Nankai Six Road Nankai District Tianjin 300102, China
Tianjin Ingenochem Technology Co.,Ltd
Contact:+86-22-23677060
Address:Hitech Green Industry Park K2-9-602, Nankai district
Shanghai Yuantai Chemical Products Co., Ltd
Contact:021--66129803
Address:Chengyin Road,Shanghai,China
Contact:+86-574-87065746
Address:10th Floor, No.787 Baizhang East Road,
Doi:10.1021/jacs.1c06557
(2021)Doi:10.1002/ardp.19723051207
(1972)Doi:10.1021/ja00757a084
(1972)Doi:10.1021/ja01253a041
(1942)Doi:10.5012/jkcs.2013.57.2.252
(2013)Doi:10.1080/14786410701877971
(2009)