4-Substituted 2-phenyl- and 2-phenyl-3-aryl pyrroles by reaction of tosyl benzyl isocyanide (TosBIC) with Michael acceptors

Article abstract of DOI:10.1080/00397919508013415

Synthesis of 2-phenyl and 2,3-diphenylpyrroles bearing at the 4 position electronwithdrawing groups by reaction of tosylbenzylisocyanide (TosBIC) with various Michael acceptors was investigated. Sodium hydride and n-butyllithium were used as deprotonating agents for the synthesis of monophenyl and diphenylpyrroles, respectively.

Full text of DOI:10.1080/00397919508013415

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Synthetic Communications: An
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4-Substituted 2-Phenyl- and
2-Phenyl-3-Aryl Pyrroles
by Reaction of Tosyl Benzyl
Isocyanide (TosBIC) with
Michael Acceptors
R. Di Santo a , R. Costi a , S. Massa a & M. Artico a
a Dipartimento di Studi Farmaceutici , Università
degli Studi di Roma “La Sapienza” , P.le Aldo Moro,
5, 00185, Roma, Italy
Published online: 23 Sep 2006.
To cite this article: R. Di Santo , R. Costi , S. Massa & M. Artico (1995) 4-Substituted
2-Phenyl- and 2-Phenyl-3-Aryl Pyrroles by Reaction of Tosyl Benzyl Isocyanide
(TosBIC) with Michael Acceptors, Synthetic Communications: An International Journal
for Rapid Communication of Synthetic Organic Chemistry, 25:6, 795-802, DOI:
10.1080/00397919508013415
To link to this article: http://dx.doi.org/10.1080/00397919508013415
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