A simple proline-based organocatalyst for the enantioselective reduction of imines using trichlorosilane as a reductant

Article abstract of DOI:10.1016/j.tet.2012.03.035

A simple and inexpensive proline-based organocatalyst was developed for the reduction of imines using trichlorosilane as a reductant. The reduction of N-aryl imines in the presence of 10 mol % of N-pivaloyl-l-proline anilide was carried out to give the co